Ultrafast and absolute quantification of SARS-CoV-2 on food using hydrogel RT-LAMP without pre-lysisArticle Published on 2023-01-152022-11-16 Journal: Journal of hazardous materials [Category] SARS, 치료기술, [키워드] Absolute quantification acute respiratory syndrome amplification cold chain Cold chain food contact infection coronavirus faster Food industry hydrogel Hydrogel RT-LAMP isothermal amplification microbe offer POCT point-of-care quantification reproducibility reverse transcription RNA RNA extraction RT-LAMP SARS-CoV-2 sensitivity specificity stability Surveillance Ultrafast detection. virus [DOI] 10.1016/j.jhazmat.2022.130050 PMC 바로가기
Long-Term Preservation of SARS-CoV-2 RNA in Silk for Downstream RT-PCR Tests다운스트림 RT-PCR 테스트를 위한 실크에서 SARS-CoV-2 RNA의 장기 보존Article Published on 2022-03-152022-09-11 Journal: Analytical Chemistry [Category] SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition ambient assays can be used Chain Reaction circumvent cold chain component Control coronavirus determined by diagnostic distribution eliminating inactivated limit limits Limits of detection mechanism Nuclease nuclease-free water offer pathogen Pathogens PCR assays polymerase chain polymerase chain reaction positive controls preservation preserved primer probe reaction reference standard reverse transcription reverse transcription polymerase chain reaction RNA room temperature RT-PCR RT-PCR reaction RT-PCR reactions SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RT-PCR severe acute respiratory syndrome Coronavirus Silk silk fibroin stability storage targets temperature Test the SARS-CoV-2 water without affecting [DOI] 10.1021/acs.analchem.2c00169 PMC 바로가기 [Article Type] Article
Effectiveness of Disinfectants Suitable for Inactivating SARS-CoV-2 at Cold-Chain Temperature저온 유통 온도에서 SARS-CoV-2 비활성화에 적합한 소독제의 효과Article Published on 2022-03-012022-09-11 Journal: Food and Environmental Virology [Category] SARS, 치료기술, [키워드] Ammonium carrier China chlorine Cold cold chain concentrations Cryogenic disinfectants Ct values disinfectant Disinfection Inactivate nucleic acid nucleic acids peracetic acid performed positive Prevent qRT-PCR SARS-CoV-2 SARS-CoV-2 RNA Spread tested treated viral nucleic acid viral nucleic acids Viral nucleic acids. virus virus RNA was used [DOI] 10.1007/s12560-022-09509-0 PMC 바로가기 [Article Type] Article
COVID-19 PCR test performance on samples stored at ambient temperature상온 보관 샘플에 대한 COVID-19 PCR 테스트 성능Article Published on 2022-03-012022-09-11 Journal: Journal of virological methods [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] ambient ambient temperature CDC cold chain Compliance condition coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 PCR test diagnostic ECDC Effect false-negative handling Infection Laboratory nasopharyngeal Oropharyngeal oropharyngeal samples outbreak pandemic Pandemics Patient PCR assay PCR positive positive Real-time PCR real-time PCR assay required Sample Sample storage. specimen storage storage condition swab sample swab samples temperature the WHO Transport Wuhan [DOI] 10.1016/j.jviromet.2021.114404 PMC 바로가기 [Article Type] Article
Phase I interim results of a phase I/II study of the IgG-Fc fusion COVID-19 subunit vaccine, AKS-452IgG-Fc 융합 COVID-19 서브유닛 백신 AKS-452에 대한 I/II상 연구의 I상 중간 결과Clinical Trial Published on 2022-02-232022-09-11 Journal: Vaccine [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 AKS-452 Alpha alpha and delta variants anti-SARS-CoV-2 Antigen caused Cell Cohort cohorts cold chain complex conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Delta variants distribution dose Endpoint Fc-fusion fusion protein healthy human IgG1 Fc IgG titer IgG titers immunogenicity assessments Infection Infectious disease Live virus mutant neutralization potency occurred Open-label pandemic phase Phase I primary endpoints profile Prophylaxis reactogenicity receiving Receptor binding domain respiratory SAE SAEs SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 viral infection secondary endpoint Secondary endpoints seroconversion rates severe acute respiratory syndrome Coronavirus single-center Single-dose skewed Spike protein subject subunit Subunit vaccine Support the SARS-CoV-2 vaccination Vaccine vaccine. Viral viral infections viral spike protein virus infection [DOI] 10.1016/j.vaccine.2022.01.043 PMC 바로가기 [Article Type] Clinical Trial
The global concern of food security during the COVID-19 pandemic: Impacts and perspectives on food securityCOVID-19 대유행 동안 식량 안보에 대한 세계적인 우려: 식량 안보에 대한 영향과 전망Article Published on 2022-02-152022-09-11 Journal: Food chemistry [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition arising artificial Artificial meat cold chain Cold chain food Contagion COVID-19 Emergency management hazard hazards Impact management measure not need pandemic Perspective Rapid rapid detection Three-dimensional-printing. [DOI] 10.1016/j.foodchem.2021.130830 PMC 바로가기 [Article Type] Article
COVID-19 Serology Control Panel Using the Dried-Tube Specimen Method건조 튜브 시편 방법을 사용한 COVID-19 혈청학 제어판Short Report Published on 2022-02-072022-09-10 Journal: The American Journal of Tropical Medicine and Hygi [Category] 진단, 치료법, [키워드] acute respiratory syndrome Antibody Units Antigen benefit binding antibody unit coded cold chain Control convalescent coronavirus COVID-19 Deterioration develop domain DTS FIVE greater IgG IgM Immunoglobulin international standard Laboratory Laboratory testing nucleocapsid offer Panel provide Quality assurance reactivity respiratory Sample serological test serology severe acute respiratory syndrome Coronavirus specimen Standard subtype the WHO total Ig was used [DOI] 10.4269/ajtmh.21-1036 PMC 바로가기 [Article Type] Short Report
The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections니클로사미드 용해도, 용해도 및 형태의 pH 의존성: COVID19, 그 변종 및 기타 바이러스 감염에 대한 잠재적으로 보편적인 점액 침투 비강 및 인후 스프레이에 대한 동기Article Published on 2022-01-012022-09-11 Journal: Pharmaceutical research [Category] 변종, 치료제, [키워드] Bioavailability cold chain Concentration concentrations contagious coronavirus COVID19 dependence dissolution distribution early treatment effective Efficacy epithelial cells Final help host cell host cell modulation Infection Local morphology motivation much lower nasal niclosamide niclosamide-solubility observé pandemic pH-dependent-dissolution polymorph precipitated Prevent Prophylactic reduce respiratory viral infections resulting sigma solubility Spectroscopy spray supernatant supersaturated solution Throat treat Universal universal nasal-throat-spray variants viral infection viral infections Viral infections. Viral load was used were measured [DOI] 10.1007/s11095-021-03112-x PMC 바로가기 [Article Type] Article
A Cold Chain-Independent Specimen Collection and Transport Medium Improves Diagnostic Sensitivity and Minimizes Biosafety Challenges of COVID-19 Molecular Diagnosis콜드 체인 독립적인 표본 수집 및 운송 매체는 진단 감도를 개선하고 COVID-19 분자 진단의 생물학적 안전성 문제를 최소화합니다Research Article Published on 2021-12-082022-09-10 Journal: Microbiology Spectrum [Category] SARS, 진단, 치료기술, [키워드] Accessibility adoption Asymptomatic biosafety bottleneck capture Care challenge Cold cold chain Collection Community contagious COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients COVID-19 testing COVID-19 transmission diagnostic diagnostic sensitivity diagnostics feasibility highlight identify inactivated India lack limit maintain medium microbial molecular Molecular diagnosis molecular diagnostics neutralize pandemic patients Prevent qPCR qRT-PCR quantitative PCR sample collection SARS-CoV-2 sensitivity significantly lower specimen specimen collection sustained symptomatic temperature threshold Transport transport medium unique unmet need urban population utility Viral Viral transmission Viral transport medium Virology virus VTM [DOI] 10.1128/Spectrum.01108-21 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Antibody Binding and Neutralization in Dried Blood Spot Eluates and Paired Plasma건혈 반점 용출액 및 짝을 이루는 혈장에서 SARS-CoV-2 항체 결합 및 중화Research Article Published on 2021-10-202022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 진단, [키워드] 384-well format acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adoption ambient ambient temperature antibodies antibody Antibody binding Antibody Response Antibody responses binding Blood cold chain cold temperatures collected convalescent coronavirus correlated COVID-19 COVID-19 pandemic Critical dried blood spot Dried blood spots ELISA Eluate enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay epitope epitope mapping equipment evaluate feature fingerstick immune response immune responses Infection invasive Longevity MOST natural infection neutralization assays Neutralizing antibodies neutralizing antibody overcome phage display plasma plasma antibody Population profile reflected respiratory responses risk SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody response SARS-CoV-2 antibody responses SARS-CoV-2 neutralization SARS-CoV-2 variant sera severe acute respiratory syndrome Coronavirus specific antibodies spot storage Support temperature vaccinated individuals vaccination variety venipuncture venous venous blood while [DOI] 10.1128/Spectrum.01298-21 PMC 바로가기 [Article Type] Research Article